Insert a new lancet in the lancet holder. It is properly positioned when it snaps into place. To remove the protective cap, twist and pull it away from the lancet. Replace the cap onto the lancet device. Twist the cap of the lancet device to set the lancet depth. Start at 2 or 3. For tougher skin, dial to a higher number. Press the plunger on the end of the device all the way down until it clicks. A yellow dot will appear and remain in the center of the clear release button.